Molecular Beacon Synthesis Companies

www www.molecular-beacons.org

---

Recent Publications from Our Group

In the November 23, 2011 issue of Cell, using our unique single-molecule imaging approach, we describe circumstances under which splicing is uncoupled from transcription. An interview conducted by Cell's editorial staff with Sanjay Tyagi about this work can be listened to at www.cell.com/../paperclip.mp3

Vargas DY, Shah K, Batish M, Levandoski M, Sinha S, Marras SAE, Schedl P, Tyagi S (2011) Single-molecule imaging of transcriptionally coupled and uncoupled splicing Cell 147, 1054-1065.

We describe a protocol for a novel method that utilizes single labeled Fluorescent In-situ Hybridization probes to image individual mRNA molecules

Batish M, Raj A, and Tyagi S (2011) Single Molecule Imaging of RNA In Situ. Methods in Molecular Biology 714, 3-11.

In collaboration with Diana Bratu and Irina Catrina at Hunter College in New York City, we published on the design parameters and applications of Locked Nucleic Acid (LNA) based molecular beacon probes to detect RNA in live cells

Bratu DP, Catrina IE, and Marras SAE (2011) Tiny molecular beacons for in vivo mRNA detection. Methods in Molecular Biology 714, 141-157.